![]() The sort of questions the doctor will ask you may include: The doctor will need to ask you questions about the rash and your general health (take a history), examine you and do some tests. How is purpura diagnosed?īecause there are so many causes, diagnosing the reason why you have developed a rash takes a bit of detective work. The seriousness of the rash depends on what is causing it. Others will resolve just by stopping the medicine, or whatever caused the rash to appear. Some are serious but manageable with treatment, such as systemic lupus erythematosus. Some of them are life-threatening, such as severe infections or bone marrow failure. Conditions causing dilution of the platelets, such as rapid transfusion of large quantities of stored blood.Haemolytic uraemic syndrome (destruction of blood cells associated with kidney disease and kidney damage). ![]() Disseminated intravascular coagulation which causes excessive blood clotting in small blood vessels).Conditions affecting the blood clotting (coagulation) system, such as:.Conditions that increase the breakdown of platelets, such as:.Medicines such as co-trimoxazole (an antibiotic) and chemicals.Cancer deposits replacing the bone marrow.Aplastic anaemia (anaemia caused by problems with production of the platelets and other blood cells by the bone marrow).Conditions resulting from problems with platelet production, such as:.Conditions that cause increased pressure, such as coughing or vomiting.Other causes, such as ageing of the skin, injury (trauma), lack of vitamin C (scurvy) and poor blood supply, especially to the legs.As a side-effect of medicines such as steroids and sulfonamides (antibiotics).Disorders of the connective tissue that connects and binds other bits of the body together, such as systemic lupus erythematosus and rheumatoid arthritis.Allergy-based conditions such as Henoch-Schönlein purpura.Severe bacterial infections such as sepsis, infection with one of the germs that cause meningitis (meningococcal disease).Conditions acquired after you were born, such as:.Infections picked up during pregnancy whilst still in the womb, such as cytomegalovirus and rubella.Pseudoxanthoma elasticum (a condition affecting the elastic tissue of the blood vessels and other parts of the body).
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